Clinical significance of the tumor markers CYFRA 21-1 and neuron-specific enolase in lung cancer

Autor:	N V Liubimova, A. V. Vasil’ev, A O Lemeshko, M. I. Davydov, Kushlinskiĭ Ne
Rok vydání:	1997
Předmět:	Pathology medicine.medical_specialty business.industry Enolase Cell General Medicine respiratory system medicine.disease General Biochemistry Genetics and Molecular Biology medicine.anatomical_structure Antigen Carcinoma Medicine Adenocarcinoma Clinical significance business CYFRA 21-1 Lung cancer
Zdroj:	Bulletin of Experimental Biology and Medicine. 123:85-87
ISSN:	1573-8221 0007-4888
Popis:	The diagnostic validity of CYFRA 21-1 and neuron-specific enolase is assessed in patients with lung cancer. Serum contents of CYFRA 21-1 and neuron-specific enolase are increased, respectively, in 74 and 67% of patients with various histological variants of lung cancer. Diagnostic sensitivity of CYFRA was 77.2% in lung cancer other than the small cell variant and 76% in small cell lung cancer. A correlation between the CYFRA content and the tumor size in patients with squamous and other than small cell lung cancer is demonstrated. In patients with spread small cell cancer, serum enolase content tends to increase compared with that in patients with localized small cell cancer. Both CYFRA and enolase are sensitive lung tumor markers in the diagnostics and evaluation of the extent of tumor spread.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::92b86b7545d89c56120dd2bf7b08d23e https://doi.org/10.1007/bf02764389 Zobrazit plný text záznamu Full text from SpringerLink