Synthesis and radioprotector activity of N-vinylpyrrolidone and 2-methyl-5-vinyltetrazole copolymers

Autor:	Yu. V. Kochkina, D. V. Eremin, V. V. Suslov, S. A. Kedik, A. V. Panov, I. V. Sakaeva
Rok vydání:	2013
Předmět:	Pharmacology chemistry.chemical_compound Monomer Chemistry Drug Discovery Radical polymerization Polymer chemistry Pharmacology toxicology N-Vinylpyrrolidone Copolymer Organic chemistry
Zdroj:	Pharmaceutical Chemistry Journal. 46:726-729
ISSN:	1573-9031 0091-150X
Popis:	Copolymers of N-vinylpyrrolidone and 2-methyl-5-vinyltetrazole with various ratios of monomer units were synthesized by radical polymerization using the injection method. The copolymerization parameters for these monomers were calculated by the Kelen―Tudos method (r1 = 14.34; r2 = 0.06) for high degrees of conversion. Copolymers with monomer-unit concentrations up to 70 ± 5 mol% were soluble in water, non-toxic, and effective as radioprotectors.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::92a5d0a8bfcb8500bb0714a6a51ee2b2 https://doi.org/10.1007/s11094-013-0879-4 Zobrazit plný text záznamu Plný text ve formátu PDF