ChemInform Abstract: Novel Inhibitors of Cell Adhesion Molecule Expression
Autor: | Norma Graber, Takao Nishi, Tracy Ebert, Dawson Bealls, Miranda Fong, Dharmpal S. Dodd, Zhongqi Shen |
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Rok vydání: | 2010 |
Předmět: | |
Zdroj: | ChemInform. 28 |
ISSN: | 0931-7597 |
DOI: | 10.1002/chin.199715137 |
Popis: | 2-Alkylsulfinyl-1,3,4-oxadiazoles have been identified as novel inhibitors of cell adhesion molecule expression on endothelial cells. These compounds have been shown to inhibit the up-regulation of ELAM-1 and VCAM-1 on activated human umbilical vein endothelial cells (HUVECs) as measured by ELISA. |
Databáze: | OpenAIRE |
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