ChemInform Abstract: Novel Inhibitors of Cell Adhesion Molecule Expression

Autor: Norma Graber, Takao Nishi, Tracy Ebert, Dawson Bealls, Miranda Fong, Dharmpal S. Dodd, Zhongqi Shen
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 28
ISSN: 0931-7597
DOI: 10.1002/chin.199715137
Popis: 2-Alkylsulfinyl-1,3,4-oxadiazoles have been identified as novel inhibitors of cell adhesion molecule expression on endothelial cells. These compounds have been shown to inhibit the up-regulation of ELAM-1 and VCAM-1 on activated human umbilical vein endothelial cells (HUVECs) as measured by ELISA.
Databáze: OpenAIRE