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Mobility is impaired in individuals with knee osteoarthritis (OA) due to pain and reduced motion of the knee joint (1,2). Treatments for knee osteoarthritis include conservative options, such as pain medication and physiotherapy, and surgical options such as knee arthroplasty. The decision to perform knee arthroplasty is often based on a patient's perception of pain (3, 4) , which is known to correlate poorly with objective outcomes (5-8). Assessment of mobility outcomes could provide objective support in the decision-making process on knee arthroplasty. However, it is currently unknown whether individuals with knee osteoarthritis receiving conservative treatment differ in terms of mobility from individuals who undergo knee arthroplasty. Therefore, this study aims to explore differences in mobility characteristics between patients with and without an indication for knee arthroplasty. We will evaluate on which mobility parameters the groups differ, and what the effect size of the difference is. 1. Woolf AD, Pfleger B. Burden of major musculoskeletal conditions. Bulleting of the World Health Organization. 2003;81(9):646-56 2. Odding E, Valkenburg HA, Stam HJ, Hofman A. Determinants of locomotor disability in people aged 55 years and over: the Rotterdam Study. Eur J Epidemiol. 2001;17(11):1033-41 3. Schmitt J, Lange T, Gunther KP, Kopkow C, Rataj E, Apfelbacher C, et al. Indication Criteria for Total Knee Arthroplasty in Patients with Osteoarthritis - A Multi-perspective Consensus Study. Z Orthop Unfall. 2017;155(5):539-48. 4. Gademan MG, Hofstede SN, Vliet Vlieland TP, Nelissen RG, Marang-van de Mheen PJ. Indication criteria for total hip or knee arthroplasty in osteoarthritis: a state-of-the-science overview. BMC Musculoskelet Disord. 2016;17(1):463 5. Fransen BL, Mathijssen NMC, Slot K, de Esch NHH, Verburg H, Temmerman OPP, et al. Gait quality assessed by trunk accelerometry after total knee arthroplasty and its association with patient related outcome measures. Clin Biomech (Bristol, Avon). 2019;70:192-6 6. Boekesteijn R, Smolders J, Busch V, Keijsers N, Geurts A, Smulders K. Objective monitoring of functional recovery after total knee and hip arthroplasty using sensor-derived gait measures. PeerJ. 2022;10:e14054 7. Bolink SA, Grimm B, Heyligers IC. Patient-reported outcome measures versus inertial performance-based outcome measures: A prospective study in patients undergoing primary total knee arthroplasty. Knee. 2015;22(6):618-23 8. Liebensteiner MC, Herten A, Gstoettner M, Thaler M, Krismer M, Bach CM. Correlation between objective gait parameters and subjective score measurements before and after total knee arthroplasty. Knee. 2008;15(6):461-6. |
