Electrochemical printing of calcium alginate/gelatin hydrogel
| Autor: | Hitoshi Shiku, Jordan Robert, Kosuke Ino, Noriko Taira |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Calcium alginate
Materials science food.ingredient Electrolysis of water General Chemical Engineering 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology Electrochemistry 01 natural sciences Gelatin 0104 chemical sciences chemistry.chemical_compound food chemistry Chemical engineering Electrode Self-healing hydrogels 0210 nano-technology Sodium alginate |
| Zdroj: | Electrochimica Acta. 281:429-436 |
| ISSN: | 0013-4686 |
| DOI: | 10.1016/j.electacta.2018.05.124 |
| Popis: | Here, we report the electrochemical printing of calcium-alginate (Ca-alginate)/gelatin hydrogel. The printing process involves placing an electrode within or above a gelatin hydrogel containing sodium alginate and CaCO3 particles. Owing to acidification resulting from water electrolysis at the electrode, Ca2+ is released from the CaCO3 particles, resulting in the formation of a Ca-alginate hydrogel within the gelatin. By scanning a probe electrode or by placing patterned electrodes in the desired locations, the hydrogel formation reaction could be made to occur at any location, with the formed Ca-alginate hydrogel being trapped within the gelatin, which acted as a supporting scaffold. Upon heating, the untreated gelatin melted, yielding patterned Ca-alginate/gelatin hydrogels. In addition, mammalian cells could be cultured successfully within the hydrogel. Finally, by stacking layers of the patterned hydrogel sequentially, three-dimensional (3D) hydrogel printing could be achieved. This method of electrochemical hydrogel printing has significant potential for use in the construction of 3D tissue organs. |
| Databáze: | OpenAIRE |
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