Cytology of Ascitic Fluid in a Patient with Metastasizing Malignant Brenner Tumor of the Ovary

Autor:	Anton Scharl, Johannes F.H. Gauwerky, A. Ahr, Georg Arnold, Serban Costa, Uwe-Jochen Göhring
Rok vydání:	1997
Předmět:	Pathology medicine.medical_specialty Histology medicine.diagnostic_test business.industry Brenner Tumor Ovary General Medicine medicine.disease Pathology and Forensic Medicine Metastasis medicine.anatomical_structure Cytopathology Cytology Biopsy medicine business Hyperchromasia Mesothelial Cell
Zdroj:	Acta Cytologica. 41:1299-1304
ISSN:	1938-2650 0001-5547
DOI:	10.1159/000333524
Popis:	Background Transitional cell ("Brenner") tumors represent about 2% of all ovarian neoplasms. Brenner tumors are almost always benign. Malignant Brenner tumors of the ovary resemble urothelial carcinomas and are extremely rare. Case A 77-year-old, white female presented with malignant Brenner tumor in both ovaries as well as lung and abdominal metastases. The cytology of the ascitic fluid revealed many activated mesothelial cells and three-dimensional cell clusters arranged in a papillary pattern. The round to oval nuclei displayed mild anisokaryosis and hyperchromasia but had a quite evenly dispersed opaque or finely granular nucleoplasm. Enfoldings of the nuclear membrane gave them the appearance of so-called coffee bean nuclei. The cytoplasm stained light bluish. Conclusion Knowledge of the cytologic features of ascitic fluid might allow a preoperative diagnosis of malignant, or at least proliferating, ovarian Brenner tumor.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9277f7ab3125b8cab72fc170e5447d40 https://doi.org/10.1159/000333524 Zobrazit plný text záznamu