Nutrigenomics: Understanding the Role of Nutrients and Gene Interactions in Periodontal Disease
| Autor: | Divya Bhat, Aparna Suraj Nellipunath, Apoorva Sokke Mallikarjunappa, Suchetha Aghanashini, Darshan B Mundinamane, Sapna Nadiger |
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| Rok vydání: | 2019 |
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| Zdroj: | Journal of Contemporary Dentistry. 9:135-140 |
| ISSN: | 2279-0217 2278-2680 |
| Popis: | Periodontal disease is a progressive inflammatory process, involving periodic destruction of periodontal attachment apparatus and loss of structures of the apparatus, essentially gingiva, periodontal ligament, cementum, and alveolar bone, ultimately resulting in loss of tooth in most susceptible patients.1Advanced knowledge on the pathogenesis of periodontal destruction and the role of nutrients on it, has increased the interest to determine the relationship between periodontal disease and nutrition.2It is also essential to know that periodontal disease risk is determined by genotype and dietary interactions.3Nutrients that play an important role in inflammatory and immune responses can in turn regulate and modulate periodontal health.4Nutrigenomics is a branch of nutritional genomics, which uses genomic tools in nutritional research to focus on the identification and understanding of the molecular-level interaction between nutrients and genomes.5It provides information on the influence of nutrition on the metabolic pathways and homeostatic control and also allows us to know the disturbances arising in this regulation, at an early stage.6This literature review provides a detailed description of the role of nutrition in periodontal disease and recommends the daily nutritional intake necessary for the prevention of periodontal disease.7How to cite this article:Nellipunath AS, Aghanashini S, Mallikarjunappa AS,et al.Nutrigenomics: Understanding the Role of Nutrients and Gene Interactions in Periodontal Disease. J Contemp Dent 2019;9(3):135–140. |
| Databáze: | OpenAIRE |
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