Obstetric and Perinatal Outcomes in Women with Type 1 Diabetes Mellitus

Autor:	Oana Sdic, Alin Albai, Romulus Timar, Bogdan Timar, Ilie Cristina, Adrian Vlad, Corina Marcela Hogea, Oana Albai
Rok vydání:	2013
Předmět:	medicine.medical_specialty Type 1 diabetes endocrine system diseases business.industry Obstetrics Diabetes mellitus nutritional and metabolic diseases Medicine business medicine.disease
Zdroj:	Romanian Journal of Diabetes Nutrition and Metabolic Diseases. 20:37-43
ISSN:	2284-6417 2068-8245
DOI:	10.2478/rjdnmd-2013-0005
Popis:	Background and aims: Pregnancy in women with type 1 diabetes mellitus (T1DM) is associated with increased risk of maternal and fetal complications. The aim of this study was to examine and to compare pregnancy outcomes between women with T1DM and a control group of non diabetic women. Material and method: The present study included all pregnancies in T1DM women followed at Diabetes Clinic, Emergency County Clinical Hospital, Timişoara, from 1990 to 2010. Results: We found a relative risk of spontaneous abortions of 1.85 (95%CI 1.01-3.39; p=0.05) and a relative risk of major congenital malformations of 4.32 (95%CI 1.55-12; p=0.005) in T1DM pregnancies compared to the control group. We also observed that the rate of stillbirth was more frequent in type 1 diabetic pregnancies (p=0.02). The offspring of T1DM women were more likely to be delivered preterm (32%) compared with the control group (9.5%). The relative risk of preterm delivery was 3.38 higher (95%CI 2.93-5.6; p
Databáze:	OpenAIRE
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