Antiphospholipid Antibodies, Haemostatic Variables and Thrombosis – A Survey of 144 Patients
| Autor: | Luigi Iannaccone, Vincenzo Brancaccio, Paul R J Ames, Stephen D.M. Pyke |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Lupus anticoagulant
medicine.medical_specialty biology medicine.diagnostic_test business.industry Hematology medicine.disease Fibrinogen Gastroenterology Venous thrombosis Von Willebrand factor immune system diseases Antiphospholipid syndrome hemic and lymphatic diseases Hemostasis Internal medicine Immunology biology.protein Medicine skin and connective tissue diseases business Partial thromboplastin time medicine.drug Blood coagulation test |
| Zdroj: | Thrombosis and Haemostasis. 73:768-773 |
| ISSN: | 2567-689X 0340-6245 |
| DOI: | 10.1055/s-0038-1653866 |
| Popis: | SummarySeveral clotting abnormalities have been put forth to explain the thrombotic tendency of the antiphospholipid syndrome, but a possible role for fibrinogen and von Willebrand factor has been poorly investigated. The present cross-sectional retrospective study evaluated the relationship of IgG anticardiolipin antibodies, lupus anticoagulants, fibrinogen and von Willebrand factor with the occurrence of arterial and venous thromboses in patients with antiphospholipid antibodies. Among the clotting assays for the detection of lupus anticoagulant, dilute Russell’s viper venom time correlated with a history of venous thrombosis more strongly than activated partial thromboplastin time (p |
| Databáze: | OpenAIRE |
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