Base and concentration effects on the product distribution in copper-promoted alkyne–azide cycloaddition: additive-free route to 5-iodo-triazoles

Autor:	Nicholas W. Smith, Sergei V. Dzyuba, Bradley P. Polenz, Shawna B. Johnson
Rok vydání:	2010
Předmět:	chemistry.chemical_classification Base (chemistry) Organic Chemistry chemistry.chemical_element Alkyne Biochemistry Copper Cycloaddition Product distribution chemistry.chemical_compound chemistry Drug Discovery Organic chemistry Azide
Zdroj:	Tetrahedron Letters. 51:550-553
ISSN:	0040-4039
Popis:	Formation of 5-iodo-triazoles in CuI-promoted cycloadditions between alkynes and azides is controlled by DMAP and low alkyne concentrations.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9233da1ac291e981f0727ad859dcf79a https://doi.org/10.1016/j.tetlet.2009.11.089 Zobrazit plný text záznamu Full Text from ScienceDirect