POLYMERS FOR THE SUSTAINED RELEASE OF MACROMOLECULES: APPLICATIONS AND CONTROL OF RELEASE KINETICS

Autor:	Rajan S. Bawa, Robert Langer, William D. Rhine, Dean S. T. Hsieh
Rok vydání:	1980
Předmět:	Solvent chemistry.chemical_classification Materials science chemistry Polymer solution Kinetics Polymer chemistry technology industry and agriculture Mixing (process engineering) Pellets Polymer Biocompatible material Macromolecule
DOI:	10.1016/b978-0-12-074450-3.50009-7
Popis:	In an earlier study, we described the first biocompatible polymeric delivery systems capable of continuously delivering macromolecules (M.W. < 1000), such as proteins, for prolonged periods (1). These systems were formed by mixing macromolecules in a polymer solution, pouring the mixture into small, conical molds, and evaporating the solvent. The resulting pellets, when exposed to aqueous medium, released macromolecules in biochemically active form for over 100 days (2).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::91e6af4fc6f9842b4635aca81cda3ac1 https://doi.org/10.1016/b978-0-12-074450-3.50009-7 Zobrazit plný text záznamu