Peptide synthesis. Part 3. Comparative solid-phase syntheses of human β-endorphin on polyamide supports using t-butoxycarbonyl and fluorenylmethoxycarbonyl protecting groups

Autor:	Robert C. Sheppard, Hazel Fox, Diana Harkiss, Eric Atherton, Mario Caviezel, Hilary Over
Rok vydání:	1983
Předmět:	Reaction conditions chemistry.chemical_classification Residue (chemistry) chemistry.chemical_compound chemistry Polyamide Peptide synthesis Organic chemistry Peptide
Zdroj:	J. Chem. Soc., Perkin Trans. 1. :65-73
ISSN:	1364-5463 0300-922X
Popis:	Solid-phase syntheses of the 31 residue peptide human β-endorphin on polar polyamide supports are described. Minimisation of acidic reaction conditions by replacement of the customary t-butoxycarbonyl and benzyl-based protecting groups by fluorenylmethoxycarbonyl and t-butyl gave a higher yield of purer product.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::91e10fff9cb1ba13a986d30b94f4d2a8 https://doi.org/10.1039/p19830000065 Zobrazit plný text záznamu