Development of a TAPE-Agar Liquid Gel Bandage
| Autor: | Kevin Adrian D. Wong, Terence P. Tumolva, Roela Feliz M. Bautista, Marin Rosette H. Tam |
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| Rok vydání: | 2020 |
| Předmět: |
Chromatography
food.ingredient Materials science Mechanical Engineering Polyethylene glycol 010402 general chemistry 01 natural sciences 0104 chemical sciences 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine food chemistry Mechanics of Materials Tannic acid Agar General Materials Science Bandage Liquid bandage |
| Zdroj: | Key Engineering Materials. 841:20-25 |
| ISSN: | 1662-9795 |
| Popis: | In this study, a liquid gel bandage for wound treatment was synthesized using a combination of tannic acid and polyethylene glycol (TAPE). Agar was added as a stabilizer based on the physical properties of the formed product. Ethanol was chosen as solvent based on the resulting drying rate and mixing consistency. The liquid bandage was characterized in terms of its drying, adhesion, and swelling. Also, its antimicrobial and cytotoxic properties were evaluated. The final formulation had a drying time of 5 minutes, a T-peel adhesion yield point of 591.6 Pa, and a swelling ratio of 64%. The gel was also observed to be anti-microbial towards both S. aureus and E. coli, as well as exhibiting cytotoxic effects. Overall, the gel proved to have comparable properties to previously studied liquid bandages yet can be produced at a significantly lower cost. |
| Databáze: | OpenAIRE |
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