RELATIONSHIP BETWEEN ARRHYTHMIAS AND A LIBERATION OF ENDOGENOUS CATECHOLAMINE CAUSED BY TOXIC DOSES OF OUABAIN IN DOGS

Autor:	Isami Shudo
Rok vydání:	1977
Předmět:	medicine.medical_specialty Chemistry Adrenalectomy medicine.medical_treatment Sympathetic nerve Endogeny Toxicology Blood pressure rise Ouabain Peripheral Endocrinology Internal medicine medicine Catecholamine Liberation medicine.drug
Zdroj:	The Journal of Toxicological Sciences. 2:239-249
ISSN:	1880-3989 0388-1350
DOI:	10.2131/jts.2.239
Popis:	A remarkable blood pressure rise associated with elevated plasma catecholamines was observed at the onset of arrhythmia when a toxic dose of ouabain was administered into dogs. The mechanism of this phenomenon may be explained as the release of endogenous catecholamines from the adrenal glands and peripheral sympathetic nerve endings brought about by a toxic dose of ouabain. Central catecholamine does not appear to be related with the above phenomenon.
Databáze:	OpenAIRE
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