A Mild and Efficient Approach to Functional Single-Chain Polymeric Nanoparticles via Photoinduced Diels–Alder Ligation
| Autor: | Peter Krolla-Sidenstein, Kim K. Oehlenschlaeger, Hartmut Gliemann, Ozcan Altintas, Kilian N. R. Wuest, Johannes Willenbacher, Christopher Barner-Kowollik |
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| Rok vydání: | 2013 |
| Předmět: |
chemistry.chemical_classification
Nitroxide mediated radical polymerization Polymers and Plastics Organic Chemistry Radical polymerization Alkyne Photochemistry Cycloaddition Styrene Inorganic Chemistry chemistry.chemical_compound chemistry Intramolecular force Polymer chemistry Materials Chemistry Copolymer Moiety |
| Zdroj: | Macromolecules. 46:8092-8101 |
| ISSN: | 1520-5835 0024-9297 |
| DOI: | 10.1021/ma4015033 |
| Popis: | We present a new ambient temperature synthetic approach for the preparation of single-chain polymeric nanoparticles (SCNPs) under mild conditions using a UV-light-triggered Diels–Alder (DA) reaction for the intramolecular cross-linking of single polymer chains. Well-defined random copolymers with varying contents of styrene (S) and 4-chloromethylstyrene (CMS) were synthesized employing a nitroxide-mediated radical polymerization (NMP) initiator functionalized with a terminal alkyne moiety. Postpolymerization modification with 4-hydroxy-2,5-dimethylbenzophenone (DMBP) and an N-maleimide (Mal) derivative led to the functional linear precursor copolymers. The intramolecular cross-linking was performed by activating the DMBP groups via irradiation with UV light of 320 nm for 30 min in diluted solution (cPolymer = 0.017 mg mL–1). The ensuing DA reaction between the activated DMBP and the Mal groups resulted in well-defined single-chain polymeric nanoparticles. To control the size of the SCNPs, random copolymer... |
| Databáze: | OpenAIRE |
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