A high-resistance-starch rice diet reduces glycosylated hemoglobin levels and improves the antioxidant status in diabetic rats
| Autor: | Shi Hong Chen, Hsing-Hsien Cheng, Wen C. Hou, Chun Kuang Shih |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Antioxidant Starch Cholesterol medicine.medical_treatment Insulin food and beverages Biology Streptozotocin medicine.disease Malondialdehyde chemistry.chemical_compound Endocrinology Postprandial chemistry Internal medicine Diabetes mellitus medicine Food Science medicine.drug |
| Zdroj: | Food Research International. 40:842-847 |
| ISSN: | 0963-9969 |
| DOI: | 10.1016/j.foodres.2007.01.015 |
| Popis: | Diabetes mellitus is a common problem in developed countries. An improved postprandial hyperglycemic peak is one of the main therapeutic targets in diabetic patients. The Wistar rats with streptozotocin (STZ)-induced diabetes were divided into cornstarch (control) and Japonica rice groups, which were fed 640 g starch/kg diets for 4 weeks. The area (means § SD) under the glucose curve of cornstarch was 173.8 § 6.9 and Japonica rice diet was 154.3 § 8.7 mmol £ min/L, and the area (means § SD) under the insulin curve of cornstarch was 12.9 § 0.1 and Japonica rice diet was 12.0 § 0.6 nmol £ min/L. The glycosylated hemoglobin levels, serum fructosamine and cholesterol concentrations in diabetic rats fed the Japonica rice diet were signiWcantly lower than the control group (P < 0.05). The decreased malondialdehyde levels and increased superoxide dismutase activity and total radical-trapping antioxidant parameter in plasma were also found in rat fed the Japonica rice diet compared to the control. These results suggested that the diet containing high-resistance-starch Japonica rice might reduce glycosylated hemoglobin levels, serum cholesterol concentrations and raised the antioxidant status in the blood. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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