Fine Needle Aspiration Cytology as a Primary Diagnostic Modality in Evaluation of Mesenchymal Lesions

Autor: Nishtha Batra, Asha. U., M. K. Umarani, Hemalatha Al
Rok vydání: 2013
Předmět:
Zdroj: Advances in Cancer: Research & Treatment. :1-8
ISSN: 2326-702X
Popis: Since mesenchymal lesions (bone and soft tissue) are heterozygous and classified on histogenetic basis, it is difficult to cytologically categorize and subtype them into specific entities. Nevertheless, the necessity for determining at least the general category of these neoplasms as benign or malignant arises since, the management of these mesenchymal neoplasms involves definitive and even radical surgery .To meet this requirement, a study was undertaken by adapting Fine Needle Aspiration Cytology (FNAC) as a primary modality for diagnosis of mesenchymal lesions. 502 FNAC smears of mesenchymal lesions were reviewed to assess if FNAC was an appropriate tool for primary evaluation of mesenchymal lesions. After excluding typical lipomas, fibrolipomas and smears with inadequate material from the study, the remaining 127 cases were taken up for the study. Histopathological correlation was available in 113 cases and only these cases were considered for calculation of various statistical indices .89 cases were cytodiagnosed as benign, 5 cases as ‘suspicious of malignancy’ and 19 cases as malignant. The diagnostic accuracy rate was 92.2%, accounting for sensitivity and specificity of 83.3% and 95.51% respectively.
Databáze: OpenAIRE