An Epidemiologic Study of Arsenic-Related Skin Disorders and Skin Cancer and the Consumption of Arsenic-Contaminated Well Waters in Huhhot, Inner Mongolia, China
| Autor: | Steven H. Lamm, Zhen-Dong Luo, Fu-Bao Bo, Ge-You Zhang, Ye-Min Zhang, Richard Wilson, Daniel M. Byrd, Shenghan Lai, Feng-Xiao Li, Michael Polkanov, Ying Tong, Lian Loo, Stephen B. Tucker, null the Inner Mongolia Cooperative Arse |
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| Rok vydání: | 2007 |
| Předmět: |
inorganic chemicals
Veterinary medicine Hyperkeratoses Epidemiologic study integumentary system business.industry Health Toxicology and Mutagenesis Ecological Modeling Environmental engineering chemistry.chemical_element Contamination Inner mongolia medicine.disease Pollution Exposure level chemistry Medicine Skin cancer business ARSENIC EXPOSURE Arsenic |
| Zdroj: | Human and Ecological Risk Assessment: An International Journal. 13:713-746 |
| ISSN: | 1549-7860 1080-7039 |
| DOI: | 10.1080/10807030701456528 |
| Popis: | Well-use histories were obtained and dermatological examinations were conducted for 3,179 of the 3,228 (98.5%) residents of 3 villages in Inner Mongolia with well water arsenic levels as high as 2,000 ppb (ug/L). Eight persons were found to have skin cancer, 172 had hyperkeratoses, 121 had dyspigmentation, 94 had both hyperkeratoses and dyspigmentation, and, strikingly, none had Blackfoot disease. All 8 subjects with skin cancer also had both hyperkeratoses and dyspigmentation. Arsenic levels were measured for 184 wells and individual well-use histories were obtained. Arsenic exposure histories were summarized as both highest arsenic concentration (highest exposure level for at least 1-year duration) and cumulative arsenic exposure (ppb-years). Sixty-nine percent of the participants had highest arsenic concentrations below 100 ppb; 71% had cumulative arsenic exposures below 2,000 ppb-years. Exposure-response analyses included frequency-weighted, simple linear regression, and most-likely estimate ... |
| Databáze: | OpenAIRE |
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