Popis: |
Eradication of Helicobacter pylori infections has proven to be difficult [2–4, 6–8, 13]. Therapy with a single or with two antimicrobials has proven ineffective as evidenced by eradication rates much below 50% [3]. Recently, combinations of three antimicrobial drugs have been shown to eradicate more than 50% of H. pylori infections. Despite these apparent successes, the results have been variable and the factors influencing effectiveness of therapy remain unclear [3, 7, 8]. In this study we evaluated the effectiveness of a combination of three antimicrobial drugs (triple therapy) for eradication of H. pylori infection with special emphasis on the factors that might predict good versus poor responses. |