Capnometry levels as an indicator of renal graft evolution in uncontrolled non-heart beating donors

Autor: D. Varillas Delgado, A.A. Mateos Rodríguez, A. Villar Arias, A. Andrés Belmonte, C. Rubio Chacón
Rok vydání: 2020
Předmět:
Zdroj: Medicina Intensiva (English Edition). 44:233-238
ISSN: 2173-5727
DOI: 10.1016/j.medine.2018.10.011
Popis: Objective The capnometry values during resuscitation are an evolutive predictor of kidneys obtained from uncontrolled non-heart beating donors. Design The study comprised a retrospective onset cohort of 37 non-heart beating donors and a validation cohort of 55 transplanted kidneys in the period 2013–2017. Scope The population served by the emergency service and referred to Hospital Universitario Doce de Octubre (Madrid, Spain) as potential uncontrolled non-heart beating donors. Patients A total of 55 renal transplant patients subjected to hemodialysis and with grafts from uncontrolled non-heart beating donors. Interventions Capnometry and capnography measurements in potential uncontrolled non-heart beating donors. Variables Capnometry values recorded initially and at transfer in hospital for comparison with the viability of the extracted kidneys; renal failure and delayed renal function. Results A total of 55 out of 74 extracted kidneys were transplanted (74.3%). The rest were ruled out due to poor perfusion or signs of ischemia. An association was observed (p = 0.016) between the capnometry values during resuscitation in the grafted kidneys (µ = 22.8 mmHg) and in the kidneys discarded for transplantation (µ = 17.35 mmHg). Conclusions Capnometry during resuscitation serves as a marker to be taken into account in relation to the viability of the transplanted organs in uncontrolled non-heart beating donors.
Databáze: OpenAIRE