Frustrated Lewis Pair Mediated Csp 3 −H Activation
| Autor: | Marc-André Courtemanche, Étienne Rochette, Frédéric-Georges Fontaine |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
010405 organic chemistry
Hydrogen bond Hydride Stereochemistry Organic Chemistry General Chemistry 010402 general chemistry Cleavage (embryo) 01 natural sciences Catalysis Frustrated Lewis pair 0104 chemical sciences chemistry.chemical_compound Shift sequence chemistry Nitrogen atom Molecule Methyl group |
| Zdroj: | Chemistry – A European Journal. 23:3567-3571 |
| ISSN: | 1521-3765 0947-6539 |
| DOI: | 10.1002/chem.201700390 |
| Popis: | The cleavage of a Csp3 -H bond by an N/B frustrated Lewis pair (FLP) is reported. Upon mild heating, the ambiphilic molecule (2-NMe2 -C6 H4 )2 BH activates the C-H bond of a methyl group in α position of a nitrogen atom to generate an unprecedented N-B heterocycle. Upon further heating, the novel species rearranges through a hydride abstraction/1,2-aryl shift sequence. The mechanistic details of these transformations are investigated by quantum mechanical calculations. |
| Databáze: | OpenAIRE |
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