Heart failure (MYHF) registry: shedding light on lipid profiles and in-hospital outcome of heart failure patients
| Autor: | W A Wan Azman, A K Abdul Ghapar, M A S K Abdul Kader, N T Ross, A Loch, A W Ramli, H H Che Hassan, S Kumar, H A Zainal Abidin, D Karthikesan, N H Mohd Amin, T K Ong, H B Liew, W Y H Wan Isa, A Mohd Ghazi |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | European Heart Journal. 44 |
| ISSN: | 1522-9645 0195-668X |
| Popis: | Funding Acknowledgements Type of funding sources: Private company. Main funding source(s): Novartis Corporation Sdn Bhd Background Heart failure is a debilitating disease associated with multiple comorbidities and poor prognosis. Dyslipidemia, is the top 5 most common comorbidities, including HF patients. Nonetheless, the lipid profiles in HF population is scarcely available and poorly understood. Purpose This report aimed to describe the lipid profiles and in-hospital outcome of hospitalized HF patients. Methods MYHF registry is a prospective, observational study of symptomatic HF patients (NYHA II-IV) hospitalized in 18 tertiary care centers in Malaysia over a period of 3 years starting in 2019. Lipid profiles will be described, and in-hospital outcome will be analyzed using univariate and multivariate models. Results In MYHF registry, 1 out of 2 hospitalized HF patients (55.7%) had ischemic heart disease, significantly higher in patients with HFrEF and HFmrEF, as compared to HFpEF (p Conclusion Dyslipidemia is highly common in general population and in HF patients. With statin therapy, only 31.4% achieved LDL-C < 1.8 mmol/L at admission. The finding highlights the unmet need for combination lipid lowering therapies to get patient to LDL-C target goal. Hospitalization also provided good opportunity of statin therapy initiation. The knowledge gained will be crucial for guiding management of HF patients with common comorbidity like dyslipidemia. |
| Databáze: | OpenAIRE |
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