132 Clinical characteristics and outcomes of a contemporary, real-world, single-centre cohort of patients with advanced heart failure
| Autor: | Matteo Pagnesi, Carlo M. Lombardi, Daniela Tomasoni, Chiara Tedino, Giuseppe Maggi, Francesco Donina, Federico Giozani, Maria Teresa Galperti, Filippo Calì, Ludovica Bognoni, Giada Colombo, Dario Cani, Riccardo M. Inciardi, Marco Metra |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | European Heart Journal Supplements. 23 |
| ISSN: | 1554-2815 1520-765X |
| Popis: | Aims An increasing number of patients with heart failure (HF) progresses to an advanced stage, characterized by persistent and sever symptoms and worse prognosis. A detailed characterization of patients with advanced HF is needed to optimize clinical management and timely refer for heart transplant or left ventricular assist device implantation. Methods and results A retrospective analysis was performed on patients with HF who were admitted to hospital or performed an outpatient visit at our centre (Spedali Civili di Brescia, Brescia, Italy) from 1 January 2020 to 31 December 2020, and who had at least one of the following high-risk characteristics: (1) previous or ongoing requirement for inotropes; (2) persisting New York Heart Association (NYHA) class III or IV and/or persistently high natriuretic peptides (BNP or NT-proBNP); (3) end-organ dysfunction, defined as worsening renal or liver dysfunction in the setting of HF; (4) ejection fraction (EF) Conclusions In our contemporary, real-world cohort of HF patients with high-risk characteristics, mid-term prognosis was poor, and the use of updated HFA-ESC criteria defining advanced HF identified a subset at increased risk of mortality. |
| Databáze: | OpenAIRE |
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