Role of Gabanergic and, or Serotonergic in the Anti-seizure Activity of Methanol Extract of Crinum jagus (J. Thomps) in Experimental Mice
Autor: | H. G. Subbair, O. J. Onaolapo, A. Y. Onaolapo, O. T. Kolawole, O. O. Abiodun, D. O. Wakeel, R. A. Adebayo-Moggaji, O. K. Wakeel |
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Rok vydání: | 2022 |
Zdroj: | European Journal of Medicinal Plants. :36-47 |
ISSN: | 2231-0894 |
Popis: | Objective: Crinum jagus is used in traditional African medicine in the treatment of epilepsy, pain and inflammations. Methods: Anticonvulsant activity was investigated using picrotoxin (PCT) and strychnine (STR) tests in experimental paradigm. Results: Crinum jagus leaf methanol extract (200, 400, and 800 mg kg−1) potentiated hexobarbitone-induced sleeping time and significantly (p |
Databáze: | OpenAIRE |
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