Laparoscopic Nissen Fundoplication Ameliorates Symptoms of Reflux, Especially for Patients with Very Abnormal DeMeester Scores
| Autor: | Sam Al-Saadi, Sharona Ross, Desiree Villadolid, Javier Gonzalez, Sarah M. Cowgill, Harold Paul, Alexander S. Rosemurgy |
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| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry musculoskeletal neural and ocular physiology medicine.medical_treatment Reflux macromolecular substances General Medicine Nissen fundoplication Preoperative care Gastroenterology Endoscopy medicine.anatomical_structure nervous system Internal medicine Severity of illness medicine Esophagus Laparoscopy Esophageal pH monitoring business |
| Zdroj: | The American Surgeon. 74:635-643 |
| ISSN: | 1555-9823 0003-1348 |
| DOI: | 10.1177/000313480807400711 |
| Popis: | Intuitively, more severe acid reflux causes more severe symptoms. This study was undertaken to correlate preoperative DeMeester scores with symptoms before and after laparoscopic Nissen fundoplication. Before fundoplication, all patients with gastroesophageal reflux disease underwent 24 to 48 hour pH testing. Before and after fundoplication, the frequency and severity of reflux symptoms were scored using a Likert scale. Four hundred and eighty-one patients underwent fundoplication and were followed for a mean of 32 months. The preoperative median DeMeester score was 41 (range 14.8 to 361.5). Before fundoplication, DeMeester scores correlated with severity of gastroesophageal reflux disease symptoms (Spearman regression analysis, P < 0.05 for all). Postoperatively, all symptom scores improved (Wilcoxon matched pairs test, P < 0.05 for all). After fundoplication, preoperative DeMeester scores did not correlate with the frequency or severity of symptoms. For patients with excessive acid reflux, reflux severity impacts the frequency and severity of symptoms before fundoplication. Laparoscopic Nissen fundoplication improves the frequency and severity of all reflux symptoms. The severity of preoperative reflux does not impact the frequency or severity of symptoms after fundoplication. Relief of excessive acid reflux, regardless of severity or degree ( i.e., DeMeester scores), ameliorates symptoms of acid reflux thereby encouraging fundoplication, especially for patients with very abnormal DeMeester scores. |
| Databáze: | OpenAIRE |
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