A cluster of congenital abnormalities particularly Down's syndrome in a small Hungarian village in 1989–90

Autor:	Zoltan Viragh, Karl Sperling, László Tímár, Andrew E. Czeizel, Erika nemes
Rok vydání:	1995
Předmět:	Pediatrics medicine.medical_specialty S syndrome Health Toxicology and Mutagenesis Public Health Environmental and Occupational Health medicine General Medicine Biology Disease cluster Pollution Teratology
Zdroj:	International Journal of Environmental Health Research. 5:281-285
ISSN:	1369-1619 0960-3123
DOI:	10.1080/09603129509356858
Popis:	A unique cluster of congenital abnormalities, particularly Down's syndrome and twins was detected in a small Hungarian village in 1989 and 1990. Of 15 livebirths, 11 had congenital abnormalities (within them 4 have affected by Down's syndrome) and 6 were twins. Different approaches of field studies and laboratory examinations indicated the germinal mutagenic and teratogenic effect of the excessive use of trichlorfon at local fish farms. Here the main experiences of this environmental abuse are summarised and the goals of ongoing studies are outlined.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::91538675f9b146bdf04377b3e0c71804 https://doi.org/10.1080/09603129509356858 Zobrazit plný text záznamu