Altered Aortic Upper Wall TDI Velocity Is Inversely Related with Left Ventricular Diastolic Function in Operated Tetralogy of Fallot

Autor: Giuseppe Mercuro, Andrea Raffaele Marras, Pier Paolo Bassareo, Luca Saba
Rok vydání: 2016
Předmět:
Zdroj: Congenital Heart Disease. 11:598-605
ISSN: 1747-079X
DOI: 10.1111/chd.12350
Popis: Objective Postoperative tetralogy of Fallot (TOF) patients often develop progressive aortic root dilatation due to an impairment in aortic elastic properties. Aims (1) to assess aortic elasticity at the level of the aortic upper wall by tissue Doppler imaging (TDI); (2) to evaluate the influence of aortic elasticity on left ventricular (LV) diastolic function in TOF patients. Design Twenty-eight postoperative TOF patients (14 males, 14 females. Mean age: 25.7 ± 1.6 years) and 28 age- and sex-matched normal subjects were examined. Aortic distensibility and stiffness index were calculated. Aortic wall systolic and diastolic velocities, LV systolic and diastolic parameters were assessed by TDI. Results Aortic distensibility was significantly lower (P = .024), and aortic stiffness index significantly higher (P = .036) in TOF patients compared to controls. E/E′ was significantly higher in TOF than in control group (P
Databáze: OpenAIRE