Two New Dy(III) and Cu(II) Coordination Polymers: Crystal Structures and Anti-liver Cancer Activity
| Autor: | Chen Li, Gui-Feng An, Bao-Hua Song |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Antitumor activity
chemistry.chemical_classification Polymers and Plastics 010405 organic chemistry Chemistry Crystal structure Polymer 010402 general chemistry medicine.disease 01 natural sciences Medicinal chemistry In vitro 0104 chemical sciences Human liver cancer chemistry.chemical_compound Materials Chemistry medicine Liver cancer Single crystal Benzoic acid |
| Zdroj: | Journal of Inorganic and Organometallic Polymers and Materials. 28:1859-1864 |
| ISSN: | 1574-1451 1574-1443 |
| Popis: | Two new three-dimensional coordination polymers (H2NMe2)[Dy4(µ3−OH)4(NMF)3(H2O)(L1)3](H2O)2 (1, NMF = N-methylformamide, H3L1 = 3,5-bis(4-(1H-tetrazol-5-yl)phenoxy)benzoic acid) and [Cu(L2)2(H2O)](H2O)2 (2, H2L2 = 4-(4-pyridyl)-isophthalic acid) have been successfully prepared using two N,O-mixed donor organic ligands. The structures of these complexes have been successfully determined by single crystal X-ray diffraction. In addition, in vitro antitumor activity of compounds 1 and 2 on four human liver cancer cells (SMMC7721, Bel-7402, MHCC97 and HCCLM3) was further determined and the results show that the two compounds showed promising activity. |
| Databáze: | OpenAIRE |
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