Methotrexate in the management of granulomatous mastitis

Autor:	Joon Kim, John M. Buckingham, Kathleen E. Tymms
Rok vydání:	2003
Předmět:	medicine.medical_specialty medicine.drug_class business.industry General Medicine Granulomatous mastitis medicine.disease Mastitis Surgery Drug withdrawal Prednisone Granuloma medicine Carcinoma Corticosteroid Methotrexate business medicine.drug
Zdroj:	ANZ Journal of Surgery. 73:247-249
ISSN:	1445-1433
DOI:	10.1046/j.1445-1433.2002.02564.x
Popis:	Granulomatous mastitis is a rare benign inflammatory breast disease that often clinically simulates carcinoma. Surgical resection of the entire lesion has been the main method of treatment but recurrence, infection, sinus formation and delayed wound healing can occur relatively commonly. Corticosteroids are also effective in recurrent or resistant cases but are associated with side-effects and relapse of disease after steroid withdrawal. A low weekly oral dose of methotrexate was used in five resistant cases after surgery plus corticosteroid. All cases achieved remission, withdrawal of corticosteroid without relapse and no methotrexate side-effect.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::91282cd6c9adf18a245fffa455264f4f https://doi.org/10.1046/j.1445-1433.2002.02564.x Zobrazit plný text záznamu Plný text