Vitamin K 3 in Feedstuffs: Antidotal Effects in Captive Anticoagulant-Resistant Rats and Mice
| Autor: | Gill Je, MacNicoll Ad |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Ecology
Difenacoum medicine.drug_class medicine.medical_treatment Anticoagulant Vitamin K3 Biology Pharmacology Toxicology chemistry.chemical_compound Menadione chemistry medicine General Earth and Planetary Sciences Rodenticide House mice Antidote Mus domesticus Ecology Evolution Behavior and Systematics Nature and Landscape Conservation General Environmental Science |
| Zdroj: | The Journal of Wildlife Management. 57:835 |
| ISSN: | 0022-541X |
| DOI: | 10.2307/3809086 |
| Popis: | Vitamin K in animal feeds may serve as an antidote to anticoagulant rodenticides. Thus, we investigated the relationship between addition of vitamin K, (menadione sodium bisulphite) to a laboratory diet at levels frequently added to animal feedstuffs, and the selection of anticoagulant resistance in Norway rats (Rattus norvegicus; hereafter called rats) and house mice (Mus domesticus; hereafter called mice). We observed increased survival in anticoagulant-resistant rats exposed to anticoagulant rodenticides; however, we did not observe increased survival in an anticoagulant-susceptible strain of rats, or in anticoagulant- resistant or susceptible mice. We observed increased survival in 3 different strains of anticoagulant-resistant rats, that were fed the anticoagulant rodenticide difenacoum |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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