Recent advances in fragile X: a model for autism and neurodegeneration

Autor:	Paul J. Hagerman, Randi J Hagerman, Michele Y. Ono
Rok vydání:	2005
Předmět:	congenital hereditary and neonatal diseases and abnormalities Fragile x Metabotropic glutamate receptor 5 business.industry Neurodegeneration medicine.disease FMR1 Fragile X syndrome Psychiatry and Mental health mental disorders medicine Dementia Autism business Neuroscience
Zdroj:	Current Opinion in Psychiatry. 18:490-496
ISSN:	0951-7367
DOI:	10.1097/01.yco.0000179485.39520.b0
Popis:	Purpose of reviewThis review will describe recent developments in the neurobiology of fragile X syndrome (FXS), the association between FXS and autism, and involvement in premutation carriers.Recent findingsMetabotropic glutamate receptor 5 (mGluR5)-coupled pathways are dysregulated in individuals w
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::911f42c7c8a912f8f03cf73f8c6d1086 https://doi.org/10.1097/01.yco.0000179485.39520.b0 Zobrazit plný text záznamu