224 One-Year Outcomes in Patients with Colorectal Malignancy and Low Functional Capacity on CPET

Autor: Tricia Tay, Ondrej Ryska, T Johnson
Rok vydání: 2022
Předmět:
Zdroj: British Journal of Surgery. 109
ISSN: 1365-2168
0007-1323
DOI: 10.1093/bjs/znac268.023
Popis: Aim Many patients with colorectal carcinoma (CRC) undergo Cardio-Pulmonary Exercise Test (CPET) to risk-stratify their suitability for surgery. This study aims to evaluate the 1-year outcomes of patients with colorectal malignancy and low functional capacity on CPET. The secondary aim is to evaluate the correlation between P-/CR-POSSUM scores and one-year outcomes. Method All patients with stage I-IIICRC who underwent CPET between January 2013-August 2020 with Anaerobic Threshold (AT) Results We included 77patients(64%males) with median age of 77(range 53–90). Thirty-one patients received best supportive care;46 underwent elective resection with median AT of 7.9(5.3–9.5)ml/min/kg and 8.7(6.4–9.9)ml/min/kg respectively(p=0.001).Of those treated surgically,9(20%)had major complications. There was no 30-day mortality. Median postoperative length of stay (LOS) was 8(3–42) days. Median overall survival(OS) among patients with surgery versus best supportive management was longer–42(8–106)months vs.25(2–59)months(p P-/CR-POSSUM scores(n=11) showed no significant correlation with major complications or LOS. One-year survival demonstrated no correlation between P-/CR-POSSUM with OS. Conclusions Surgical treatment of CRC showed survival benefit and should be considered for patients with low functional capacity. Due to our small sample size, P-/CR-POSSUM were not correlated with major complications, LOS and OS.
Databáze: OpenAIRE