Enzyme Reactors Consisting of Matrix-Bound or Entrapped Red Cell Ghosts
| Autor: | G. Schmer |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
chemistry.chemical_classification
Chromatography Biomedical Engineering Medicine (miscellaneous) Substrate (chemistry) Bioengineering General Medicine In vitro Biomaterials Cell membrane chemistry.chemical_compound medicine.anatomical_structure Enzyme Membrane chemistry Sephadex In vivo medicine Agarose |
| Zdroj: | Artificial Organs. 4:272-274 |
| ISSN: | 1525-1594 0160-564X |
| DOI: | 10.1111/j.1525-1594.1980.tb01866.x |
| Popis: | Potent enzyme reactor systems could be synthesized using red cell ghost membranes containing urease and coval-ently binding these “semi-artificial” cells to polydextran gels (Sephadex) or entrapping them in agarose gel. In vitro studies as well as in vivo studies in sheep indicate excellent physicochemical stability of the system. Limitations of the method include insufficient diffusion of certain substrates through the cell membrane, or a tight binding of the substrate to carrier proteins. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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