Tissue Eosinophils of Rat under the Influence of Gysteine, Lysine and X-Irradiation1
| Autor: | Holsti Lr, Rytoemaa T |
|---|---|
| Rok vydání: | 1965 |
| Předmět: |
chemistry.chemical_classification
0303 health sciences medicine.medical_specialty Physiology Lysine Biology Eosinophil 3. Good health Amino acid 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Endocrinology Biochemistry chemistry 030220 oncology & carcinogenesis Internal medicine medicine Stomach tube Duodenum Irradiation Cortisone 030304 developmental biology medicine.drug Cysteine |
| Zdroj: | Acta Physiologica Scandinavica. 63:370-376 |
| ISSN: | 0001-6772 |
| DOI: | 10.1111/j.1748-1716.1965.tb04076.x |
| Popis: | Cysteine and lysine were given to rats by stomach tube either alone or before whole body irradiation and the tissue eosinophils were counted. Repeated daily administration of cysteine and lysine for a week caused a significant decrease in the eosinophil count of the skin, duodenum and colon. Short term amino acid treatment caused no changes in the tissue eosinophil count. Whole body irradiation alone and after amino acid pre-treatment also caused a significant decline in the tissue eosinophil count. This concurs with observations that long-term treatment with ACTH and cortisone lowers the number of tissue eosinophils (Wegelius and Teir 1958, Rasanen 1961). The principal extra-medullary amount of eosinophils of the organism is in the tissues. The significance of these cells for the organism is that they constitute one of its defensive and protective mechanisms (Rytomaa 1960). There seems to be a relationship between the number of tissue eosinophils and the radio-protective effect of cysteine and lysine established earlier (Holsti 1960). |
| Databáze: | OpenAIRE |
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