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Department of Chemistry. Saurashtra University, Rajkot-360 005, India E-mail : drarparikh@yahoo.com Manuscript received 11May 2001, revised 22 April 2002. accepted 17 August 2002 2-Acetylbenzimidazole (1) on condensation with various aldehydes yields the chalcones (2a-1) which on cyclization with thiourea/urea in ale. KOH furnish the corresponding 2-imlno-4-(benzimidazol-2'-yl)-6-aryl-6H-2,3-dibydro-1,3-thiazinesll,3-oxozines (3a-1, 4a-1). The compounds have been evaluated for their antibacterial and antifungal activities. |
