Structural, Morphological and Biological Features of ZnO Nanoparticles Using Hyphaene thebaica (L.) Mart. Fruits
| Autor: | Hamza Elsayed Ahmed Mohamed, Malik Maaza, Dania Zia, Mokhotjwa Simon Dhlamini, Shakeeb Afridi, Zabta Khan Shinwari, Ali Talha Khalil |
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| Rok vydání: | 2020 |
| Předmět: |
Polymers and Plastics
education Zincite chemistry.chemical_element 02 engineering and technology Zinc 010402 general chemistry 01 natural sciences symbols.namesake Materials Chemistry MTT assay Surface plasmon resonance Fourier transform infrared spectroscopy Hyphaene thebaica High-resolution transmission electron microscopy biology Chemistry technology industry and agriculture 021001 nanoscience & nanotechnology biology.organism_classification 0104 chemical sciences visual_art symbols visual_art.visual_art_medium 0210 nano-technology Raman spectroscopy Nuclear chemistry |
| Zdroj: | Journal of Inorganic and Organometallic Polymers and Materials. 30:3241-3254 |
| ISSN: | 1574-1451 1574-1443 |
| Popis: | Pure zinc oxide NPs (ZnO NPs) have been synthesized using a simple eco-friendly approach using fruit extracts of Hyphaene thebaica. XRD pattern indicated zincite and highly crystalline phase of ZnO NPs. UV–Vis spectrum revealed surface plasmon resonance at 372 nm and bandgap of 3.36 eV. FTIR spectrum indicated characteristic Zn–O vibration at 450 cm−1. HRTEM images indicated particle size in the range of 8–23 nm having a quasi spherical morphology. Raman shift was observed at 297 cm−1, 405 cm−1 and 548 cm−1. Excellent protein kinase (PK) inhibition and varying antimicrobial potential against different bacterial and fungal strains is reported. E. coli and A. flavus were found as the most susceptible microbial strains. Hemocompatability of the ZnO NPs was revealed. ZnO NPs indicated a dose dependant cytotoxicity. MTT assay revealed a median lethal concentration (IC50) of 106 µg/mL against Leishmania tropica. Different antioxidant assays indicated the antioxidant potential of ZnO NPs. Hyphaene thebaica mediated ZnO NPs revealed excellent therapeutic performance and can used as a potential candidate for diverse biomedical applications. |
| Databáze: | OpenAIRE |
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