Confocal spectroscopy allows investigation of Photofrin bleaching kinetics during photodynamic therapy

Autor:	Thomas H. Foster, Soumya Mitra
Rok vydání:	2004
Předmět:	genetic structures business.industry Chemistry Confocal medicine.medical_treatment Kinetics Photodynamic therapy Fluorescence Fluorescence spectroscopy law.invention Optics Confocal microscopy law medicine Biophysics Photosensitizer sense organs Spectroscopy business
Zdroj:	Frontiers in Optics 2004/Laser Science XXII/Diffractive Optics and Micro-Optics/Optical Fabrication and Testing.
Popis:	We examine the bleaching kinetics of the photosensitizer Photofrin® using spectrally-resolved fluorescence measurements in optical sections of multicell tumor spheroids during photodynamic therapy. The results suggest that Photofrin photodegrades via two simultaneous bleaching mechanisms, and their relative importance is dependent on the initial Photofrin concentration.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::905f9af2cac692ba2c90d06ba26fa820 https://doi.org/10.1364/fio.2004.ftug39 Zobrazit plný text záznamu