Atrial Septal Defect with Rheumatic Mitral Regurgitation: A Rare Association in a Nigerian Child
| Autor: | U U Onakpoya, Oluwakemi Tolu Adegoke, AT Adenekan, Olugbenga Olalekan Ojo, Muyiwa Afolabi Owojuyigbe, John A.O. Okeniyi |
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| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Mitral regurgitation Heart disease business.industry medicine.medical_treatment Perforation (oil well) Mitral valve replacement Foramen secundum medicine.disease medicine.anatomical_structure Internal medicine Infective endocarditis Mitral valve cardiovascular system medicine Cardiology cardiovascular diseases Mitral valve regurgitation business |
| Zdroj: | International Journal of Cardiovascular and Thoracic Surgery. 5:60 |
| ISSN: | 2575-4866 |
| Popis: | Atrial septal defect (ASD) coexisting with mitral valve regurgitation has been described in literature with various aetiologies and pathophysiologic mechanisms. Mitral valve lesions coexisting with an ASD could either be congenital or acquired. The most prominent congenital mitral valve pathology is a cleft in the anterior leaflet of the mitral valve, as seen in patients with partial atrio-ventricular septal defects. Acquired mitral valve lesions include, hemodynamic induced annular dilatation resulting in significant mitral regurgitation, iatrogenic leaflet perforation and coexisting diseases such as infective endocarditis or rheumatic valve disease. However, the aetiology of the mitral valve regurgitation being due to rheumatic heart disease is uncommon. We report the case of a 12-year-old female who presented with easy fatigability, palpitation and a precordial bulge dating about 2 years. Examination revealed cardiac murmurs in the apex and pulmonary areas and transthoracic echocardiography confirmed the presence of an Ostium Secundum ASD and features of severe rheumatic mitral valve regurgitation. Child was initially placed on medications which included diuretics and an Angiotensin converting enzyme inhibitor ACEi, before she eventually had surgical closure of ASD and mitral valve replacement. The purpose of this case report is to highlight the symptomatology, diagnosis and treatment of this rare association, particularly in our environment. |
| Databáze: | OpenAIRE |
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