| Popis: |
We have shown that triterpene glycosides of the Far Eastern edible holothurian Cucumaria japonica (monosulfated subfractions A2 and A4, disulfated subfraction A6, trisulfated subfraction A7, and the total fraction of monosulfated glycosides including subfractions A0, A1, A2, and A4) inhibited growth of the main root of Cucumis sativus seedlings. Cucumariosides were arranged as follows according to their inhibitory activity: subfraction A2 (ED50 = 53.1 ± 3.6 μg/ml) > total fraction of monosulfated glycosides (ED50 = 127.4 ± 5.8 μg/ml) > subfraction A4 (ED50 = 346.5 ± 15.2 μg/ml) > subfraction A6 (ED50 = 375.7 ± 17.2 μg/ml) > subfraction A7 (ED50 = 539.4 ± 11.5 μg/ml). The average length of the main root decreased with the increase of glycoside concentrations as a result of a growing amount of seedlings with low germination capacity and the absence of seedlings with high germination capacity. |
