First synthesis of carbocyclic oligothymidylates

Autor:	Janos Sagi, J. Szecsi, Attila Szemzo, L. Ötvös
Rok vydání:	1990
Předmět:	Deoxyribonucleoside chemistry.chemical_compound chemistry Cyclitol Phase (matter) Organic Chemistry Drug Discovery Organic chemistry Thymidine Biochemistry High-performance liquid chromatography Desoxyribonucleoside
Zdroj:	Tetrahedron Letters. 31:1463-1466
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)88833-4
Popis:	5'-O-(dimethoxytrityl)-(+)-carbocyclic thymidine 1 is converted into different 3'-substituted intermediates 2a-c following standard procedures. From these compounds stereochemically pure carbocyclic oligothymidylates 4 are obtained using solid phase synthetic methods.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::904e262f30cebca0d949107bb3fc8b8a https://doi.org/10.1016/s0040-4039(00)88833-4 Zobrazit plný text záznamu