Electrospun poly(L-lactic)acid/nanoalumina (PLA/Al2O3) composite fiber mats with potential biomedical application — Investigation of cytotoxicity

Autor:	Jadwiga Dudkiewicz-Wilczyńska, Tomasz Ciach, E. Radziun, Patrycja Kurtycz, Magdalena Roslon, Elżbieta Anuszewska, K. Nowak, Andrzej Olszyna, A. Kunicki
Rok vydání:	2013
Předmět:	Poly l lactic acid Materials science Polymers and Plastics General Chemical Engineering Composite number technology industry and agriculture General Chemistry Electrospun fiber Fiber Composite material Cytotoxicity In vitro biocompatibility Electrospinning
Zdroj:	Fibers and Polymers. 14:578-583
ISSN:	1875-0052 1229-9197
DOI:	10.1007/s12221-013-0578-5
Popis:	PLA fibrous mats containing nanoalumina filler were fabricated by electrospinning method. The morphology of the mats was characterized by SEM, and TEM. In vitro biocompatibility of the electrospun fiber mats was also evaluated. Indirect cytotoxicity evaluation of the fiber mats with human skin fibroblasts revealed that the materials were non-toxic to living cells. The cells cultured on the fibrous mat exhibited normal cells shapes and were integrated well with surrounding fibers. The obtained results confirmed the potential for use of the electrosupun PLA/Al2O3 fiber mats for biomedical application.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9046504bb2ab368e079e40468f4fcfa9 https://doi.org/10.1007/s12221-013-0578-5 Zobrazit plný text záznamu Full text from SpringerLink