C21 steroidal glycosides from Cynanchum taihangense
| Autor: | Dan Zhao, Yue-Hu Pei, Shao-Fei Chen, Shan-Shan Su, Ming-Xu Tang, Gang Chen, Ying-Ying Si, Hai-Feng Wang, Yu-Bo Wang, Xia-Nan Sang |
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| Rok vydání: | 2017 |
| Předmět: |
Pharmacology
biology Steroidal glycosides 010405 organic chemistry Chemistry Stereochemistry Organic Chemistry Pharmaceutical Science General Medicine Cynanchum biology.organism_classification 01 natural sciences Nmr data 0104 chemical sciences Analytical Chemistry Human tumor 010404 medicinal & biomolecular chemistry chemistry.chemical_compound Aglycone Complementary and alternative medicine Cell culture Drug Discovery Molecular Medicine Cytotoxic T cell Cytotoxicity |
| Zdroj: | Journal of Asian Natural Products Research. 20:263-269 |
| ISSN: | 1477-2213 1028-6020 |
| DOI: | 10.1080/10286020.2017.1329302 |
| Popis: | Two new C21 steroidal glycosides, cynataihosides E (1) and F (2), together with a known one, sublanceoside H2 (3), were isolated from Cynanchum taihangense. The aglycone of cynataihoside F (2) was also a new compound. Their structures were elucidated on the basis of NMR spectroscopic data, HR-ESI-MS analysis, and chemical evidence. Their cytotoxic activities against three human tumor cell lines (HL-60, THP1, and Caco2) were reported. |
| Databáze: | OpenAIRE |
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