Synthesis of N-Derivatives of Cytisine, Anabasine, and Salsoline Alkaloids with Pharmacophore 3-Aminopyridine-2(1H)-one and 5-Methyl-7-phenyloxazole[5,4-b]pyridine Cycles

Autor:	Ivan V. Kulakov, T. M. Seilkhanov, D. N. Ogurtsova, I. V. Palamarchuk
Rok vydání:	2019
Předmět:	3-Aminopyridine 010405 organic chemistry Anabasine General Chemistry 010402 general chemistry 01 natural sciences Medicinal chemistry 0104 chemical sciences chemistry.chemical_compound Cytisine chemistry Salsoline Alkaloids Pyridine Nucleophilic substitution Pharmacophore Acetamide
Zdroj:	Russian Journal of General Chemistry. 89:2487-2491
ISSN:	1608-3350 1070-3632
DOI:	10.1134/s1070363219120259
Popis:	The reaction of nucleophilic substitution of 2-chloro-N-(6-methyl-2-oxo-4-phenyl-1,2-dihydropyridin-3-yl)acetamide and 2-(chloromethyl)-5-methyl-7-phenyloxazolo[5,4-b]pyridine with cytisine, anabasine, and salsoline alkaloids has afforded the corresponding derivatives. Structure of the obtained compounds has been confirmed by means of 1H and 13C NMR spectroscopy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::904040ffdb2023323a943dd6d34acd59 https://doi.org/10.1134/s1070363219120259 Zobrazit plný text záznamu Plný text ve formátu PDF