Effect of buspiron on formation of acquired helplessness
Autor: | A. V. Toloknov, N. K. Khitrov, V. P. Fisenko, N. A. Averkina |
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Rok vydání: | 1998 |
Předmět: | |
Zdroj: | Bulletin of Experimental Biology and Medicine. 126:896-898 |
ISSN: | 1573-8221 0007-4888 |
Popis: | By decreasing anxiety and emotional stress, buspiron in doses of 1 and 5 mg/kg decelerates the formation of instrumental defense reflex and increases the incidence of acquired helplessness in rats trained under conditions of highly indefinite environment. Buspiron in a dose of 0.5 mg/kg apparently does not affect the optimal emotional background, thus promoting attaining the goal of conditioned reflex activity and not leading to an increase in the incidence of acquired helplessness. |
Databáze: | OpenAIRE |
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