Structure-function relationship of polypeptide toxins: modifying gating mechanism of sodium channel

Autor:	S. E. Odinokov, A. A. Nabiullin, G. B. Elyakov, E. P. Kozlovskaya
Rok vydání:	1989
Předmět:	biology Biochemistry Chemistry General Chemical Engineering Sodium channel Structure function Biological activity General Chemistry Gating Sea anemone biology.organism_classification Peptide sequence
Zdroj:	Pure and Applied Chemistry. 61:497-500
ISSN:	1365-3075 0033-4545
DOI:	10.1351/pac198961030497
Popis:	Sea anemone toxins are systematically classified according to amino acid sequence, topography of hydrophobic regions and known pharmacological and immunochemical activi- ties. On basis of above properties these toxins are divided into two groups. The significance of each property is dis- cussed in view of structure-function relationship. It is shown that pharmacological activity of sea anemone toxins correlates with topography of hydrophobic regions.
Databáze:	OpenAIRE
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