Effect of suppository bases on rectal absorption rate of drugs

Autor:	A.J.M. Schoonen, A. Fens V. D. Heeuy, T. Huizinga, Ada G. G. Stuurman-Bieze, L. M. Peeters-Udding
Rok vydání:	1980
Předmět:	Pharmacology Absorption rate chemistry.chemical_compound Chromatography Rectal Absorption Chemistry Pharmaceutical Science Organic chemistry Pharmacology (medical) Suppository Sodium salt Benzoic acid
Zdroj:	Pharmaceutisch Weekblad Scientific Edition. 2:1680-1686
ISSN:	1573-739X 0167-6555
Popis:	Thein vitro release rate andin vivo absorption rate from various suppository bases was measured for benzoic acid (soluble in lipid, moderately soluble in water) and its sodium salt (very soluble in water, insoluble in lipid). Differences in the absorption rate due to a supposed unequal spreading of the basein vivo could not be detected.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8ffec8d96d283bb54cec3acf23953926 https://doi.org/10.1007/bf02273441 Zobrazit plný text záznamu