Preparation of thermosensitive hydrogel (PP-g-NIPAAm) with one–off switching for controlled release of drugs

Autor: Yinjuan Xu, Borong Bao, Shiru Zhou, Zue-Teh Ma, Jie Chen, Wu Minghong
Rok vydání: 1999
Předmět:
Zdroj: Radiation Physics and Chemistry. 56:341-346
ISSN: 0969-806X
DOI: 10.1016/s0969-806x(99)00196-6
Popis: A novel thermosensitive hydrogel with high mechanical strength was obtained by grafting N-isopropylacrylamide (NIPAAm) onto polypropylene using a preirradiation grafting method. The effect of radiation dose, dose rate, grafting temperature and reaction time on the grafting degree and properties of swelling-deswelling is discussed. Water absorption of the grafted polypropylene film could be switched on and off swiftly by control of temperature. The microstructure of grafted ultra thin porous PP film was studied with scanning electron microscope. (C) 1999 Elsevier Science Ltd. All rights reserved.
Databáze: OpenAIRE