Polymer Design and Development

Autor: Cole A. DeForest, Christopher K. Arakawa
Rok vydání: 2017
Předmět:
DOI: 10.1016/b978-0-12-802734-9.00019-6
Popis: A growing interest to probe and direct stem cell fate has fueled the ongoing development of a wide variety of polymer-based platforms for in vitro culture. Biomaterials with unique chemical and physical properties are afforded through careful selection of composition and can be engineered to mimic critical aspects of the native extracellular matrix. This chapter highlights recent progress in polymer design and development for 3D stem cell culture, comparing the advantages of both naturally and synthetic-based precursors. Special attention is given to natural materials derived from polysaccharides, peptides, and proteins, as well as smart synthetic polymer systems that exhibit responsiveness to environmental stimuli (e.g., electricity, temperature, enzyme, light, heat, pH).
Databáze: OpenAIRE