Adequacy of sulfur amino acid intake in infants receiving parenteral nutrition
| Autor: | Russell W. Chesney, Michael L. Christensen, Richard A. Helms, Michael C. Storm |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty Taurine Nutrition and Dietetics Methionine Endocrinology Diabetes and Metabolism Clinical Biochemistry Cystine Gestational age Reference range Biochemistry Amino acid Excretion chemistry.chemical_compound Parenteral nutrition Endocrinology chemistry Internal medicine medicine Molecular Biology |
| Zdroj: | The Journal of Nutritional Biochemistry. 6:462-466 |
| ISSN: | 0955-2863 |
| DOI: | 10.1016/0955-2863(95)00077-d |
| Popis: | Taurine and cysteine are considered essential nutrients for the infant receiving parenteral nutrition (PN). To define the adequacy of sulfur amino acid content in a pediatric amino acid formulation, evaluation of urinary excretion, fractional excretion, and balance studies for taurine, total (free + bound) cyst(e)ine (cysteine + cystine), and methionine were completed under steady-state conditions of energy and protein intake in 18 preterm infants receiving PN. These infants had a mean gestational age of 34.5 ± 2.4 weeks, postnatal age of 19 ± 18 days, weighed 2.1 ± 0.5 kg, and received 100 ± 22 kcal/kg/day and 2.8 ± 0.1 g/kg/day of amino acids. Plasma concentrations for the sulfur-containing amino acids were within the reference range; however, the excretion and fractional excretion of taurine (3.7 ± 7.8 mg/kg/day, 17 ± 15%) and cyst(e)ine (12.0 ± 7.1 mg/kg/day, 33 ±19%) were at the upper limits of normal reported experience. Methionine excretion (0.9 ± 1.0 mg/kg/day) and fractional excretion (16 ± 22%) were within normal reported experience. For taurine, fractional excretion inversely correlated with weight at the time of study ( r = −0.59, P |
| Databáze: | OpenAIRE |
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