AB0822-HPR Correlation of psychological state with patient global assessment in patients with rheumatoid arthritis

Autor: Yasushi Miura, K. Maeda, T. Nakanishi, H. Nakahara, C. Yukioka, M. Fusama, Takashi Kuroiwa, N. Murata, N. Takai, K. Yukioka, M. Yukioka, K. Higashi, T. Kuritani, Hajime Sano, M. Inoue
Rok vydání: 2013
Předmět:
Zdroj: Annals of the Rheumatic Diseases. 72:A1091.2-A1091
ISSN: 1468-2060
0003-4967
DOI: 10.1136/annrheumdis-2013-eular.3144
Popis: Background Patient global assessment (PGA) and evaluator global assessment (EGA) often differ in their perceptions in patients with rheumatoid arthritis (RA). Objectives The purpose of this study was to examine the correlation of psychological state on PGA and EGA in patients with RA. Methods Patients with RA were enrolled from Yukioka Hospital and NTT West Osaka Hospital, in Japan. The patients were divided to PGA remission group (PGA= 1). The patients were also divided to EGA remission group (EGA= 1). Disease activity was assessed with swollen joint counts (SJC), tender joint counts (TJC) and clinical disease activity index (CDAI). Depression was assessed with the Hospital Anxiety and Depression Scale-anxiety (HADS-A), anxiety with the State-Trait Anxiety Inventory (STAI) and sleep disturbance with Pittsburgh Sleep Quality Index (PSQI). These data were compared between 2 groups in PGA and EGA, respectively. The data was analyzed using Wilcoxon signed-rank test. Results One hundred twelve patients (18 males and 94 female) were assessed. Baseline characteristics were as follows: median [range] of age (55.5, [26-83] years old), duration (8.59, [0.25-48] years), SJC (1, [0-25]), TJC (1, [0-17]), PGA (19, [0-84]), EGA (14, [0-88]) and CDAI (6.85, [0-54.2]), respectively. There was no significant difference in age, duration and PSL dosage between PGA remission group (n=35) and non-depression group (n=77) (p=0.7727, p=0.5446, p=0.1516, respectively). Similarly, there was no significant difference between EGA remission group (n=38) and non-remission group (n=74) in age, duration and PSL dosage (p=0.6804, p=0.3565, p=0.0548, respectively). SJC, TJC, EGA and CDAI were significantly lower in PGA remission group(p Conclusions The discrepancy between PGA and EGA in patients with RA might be partially explained by the difference of psychological state. This study suggests that supports for psychological state may be effective for improvement of PGA. Disclosure of Interest None Declared
Databáze: OpenAIRE